- Editorial and Podcast in Science on pregnancy and COVID: Some quotes:
- Protect your pregnant patients. The first ones who need the masks are pregnant women. The first to avoid social contact should be pregnant women.
- According to CDC database on > 8000 COVID + pregnancy: …. 50% more likely to end up in intensive care units (ICUs) than their nonpregnant peers. Pregnant women were also 70% more likely to need ventilators, although they were no more likely to die.
- Also in the postpartum: 3 X more risk on complications.
- But no indication of birth defects in newborns: although placental circulation isq sometimes disturbed by COVID: SARES-CoV-2 is essentially non- blood borne, hence apparently no (or much less?) risk than e.g. rubella or CMV (which are blood-borne).
- Lingering viruses: the story of a young lady, Natalie Forouzad, caught in her parent’s basement, because of persistent COVID-19 PCR positivity is the background to remind us that other viruses, which usually have an acute self-limiting course (Flu, ZIKA, EBOLA, measles…) sometimes stay in the body for a long time. In some cases, they have been shown to elicit complications (e.g. subacute sclerosing panencephalitis in case of measles) or can still be infectable (e.g. ZIKA or EBOLA from a semen “sanctuary”). A low grade persistence (e.g. in association with foilicular dendritic cells in the lymph nodes) may also continuously stimulate specific immune responses , resulting in permanent re-infection immunity. In the case of SARS-CoV-2, the debate whether or not infectious virus could be “shedded” is ongoing. So not clear if people should remain in isolation. As discussed last week, measurement of subgenomic RNA (as a signh of replication-competent virus) could be a solution?
- Mental problems by COVID: read the experience from a colleague in Boston in the Annals: she had a “mild” COVID…. For those who believe we should stop emphasizing COVID, “because it just kills people who would die soon anyway”
- On the other hand there is collateral damage: because the COVID pandemic has absorbed most medical capacity in North and South for many months….
- In the North: more and more reports of negative effects on the care for non-communicable diseases, raising morbidity and mortality of cardiovascular diseases and cancer
- In the South (Nature 12 August) : COVID-19 has turned the clock back years, if not decades, in the fight against infectious diseases. AIDS TB and malaria deaths could double due to COVID
- And another review (provided by a colleague) that children are not so “innocent” after all…. See the practical advice for reopening schools on p.14 and 15….
29 Sept 2023 Episode 351 Episode 351: Vaginal bleedings and menstrual disturbances in relation to COVID infection and vaccines
> More info
14 Sept 2023 Episode 349 Update on BA.2.86 and other variants in view of the upcoming XBB.1.5 booster
> More info
20 July 2023 Episode 340 Asymptomatic SARS-CoV-2, long COVID and vaccination revisited: genetics and evidence for “Long Vax”?
> More info